Function and Biology Details
Reaction catalysed:
Cleaves proteins of the adenovirus and its host cell at two consensus sites: -Yaa-Xaa-Gly-Gly-|-Xaa- and -Yaa-Xaa-Gly-Xaa-|-Gly- (in which Yaa is Met, Ile or Leu, and Xaa is any amino acid).
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Protease and Protease cofactor (preferred)
PDBe Complex ID:
PDB-CPX-136670 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protease
Molecule details ›
Chain: A
Length: 204 amino acids
Theoretical weight: 23.11 KDa
Source organism: Human adenovirus 2
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: Adenovirus endoprotease
Structure domains: Adenoviral Proteinase; Chain A
Length: 204 amino acids
Theoretical weight: 23.11 KDa
Source organism: Human adenovirus 2
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P03252 (Residues: 1-204; Coverage: 100%)
Sequence domains: Adenovirus endoprotease
Structure domains: Adenoviral Proteinase; Chain A
Protease cofactor
Molecule details ›
Chain: B
Length: 11 amino acids
Theoretical weight: 1.35 KDa
Source organism: Human adenovirus 2
Expression system: Not provided
UniProt:
Length: 11 amino acids
Theoretical weight: 1.35 KDa
Source organism: Human adenovirus 2
Expression system: Not provided
UniProt:
- Canonical: P03274 (Residues: 240-250; Coverage: 4%)
