› 1o8v

X-ray diffraction
1.6Å resolution

The crystal structure of Echinococcus granulosus fatty-acid-binding protein 1

Released:
DOI: 10.2210/pdb1o8v/pdb
PDB entry 1o8v coloured by chain, front view.
PDB entry 1o8v coloured by chain, side view.
PDB entry 1o8v coloured by chain, top view.
Source organism: Echinococcus granulosus
Primary publication:
The crystal structure of Echinococcus granulosus fatty-acid-binding protein 1.
Jakobsson E, Alvite G, Bergfors T, Esteves A, Kleywegt GJ
Biochim Biophys Acta 1649 40-50 (2003)
PMID: 12818189

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169791 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein homolog 1 Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.13 KDa
Source organism: Echinococcus granulosus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q02970 (Residues: 1-133; Coverage: 100%)
Gene names: DF1, FABP1
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand PLM 1 x PLM
1 modified residue:
Ligand CSO 1 x CSO

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21
Unit cell:
a: 28.714Å b: 54.834Å c: 38.691Å
α: 90° β: 100.34° γ: 90°
R-values:
R R work R free
0.174 0.172 0.214
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Invertebrate intracellular fatty acid binding proteins.
Esteves et al. (2006)
3 more

8 mentions without citation

Analysis of the distribution of functionally relevant rare codons.
Widmann et al. (2008)
7 more