1obg

X-ray diffraction
2.05Å resolution

SAICAR-synthase complexed with ATP

Released:

Function and Biology Details

Reaction catalysed:
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-151042 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoribosylaminoimidazole-succinocarboxamide synthase Chain: A
Molecule details ›
Chain: A
Length: 305 amino acids
Theoretical weight: 34.52 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P27616 (Residues: 2-306; Coverage: 100%)
Gene names: ADE1, YAR015W
Sequence domains: SAICAR synthetase
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X31
Spacegroup: P212121
Unit cell:
a: 69.77Å b: 74.19Å c: 76Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.166 0.206