Function and Biology Details
Reactions catalysed:
[a protein]-serine/threonine phosphate + H(2)O = [a protein]-serine/threonine + phosphate
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
- Protein-tyrosine phosphatase-like
- Dual specificity protein phosphatase domain
- Dual specificity/tyrosine protein phosphatase, N-terminal
- Protein-tyrosine phosphatase, active site
- Tyrosine-specific protein phosphatases domain
- Protein-tyrosine phosphatase, catalytic
- Dual specificity phosphatase, catalytic domain
- Dual-specificity phosphatase CDC14, C-terminal
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Dual specificity protein phosphatase CDC14B (preferred)
PDBe Complex ID:
PDB-CPX-130081 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dual specificity protein phosphatase CDC14B
Molecule details ›
Chain: A
Length: 348 amino acids
Theoretical weight: 40.48 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains:
Length: 348 amino acids
Theoretical weight: 40.48 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
O60729 (Residues: 39-386; Coverage: 70%)
Sequence domains:
- Dual specificity protein phosphatase, N-terminal half
- Dual specificity phosphatase, catalytic domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF
Spacegroup:
C2
Expression system: Spodoptera frugiperda
