› 1okc

X-ray diffraction
2.2Å resolution

structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside

Released:
DOI: 10.2210/pdb1okc/pdb
PDB entry 1okc coloured by chain, front view.
PDB entry 1okc coloured by chain, side view.
PDB entry 1okc coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside.
Pebay-Peyroula E, Dahout-Gonzalez C, Kahn R, Trézéguet V, Lauquin GJ, Brandolin G
Nature 426 39-44 (2003)
PMID: 14603310

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136100 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP/ATP translocase 1 Chain: A
Molecule details ›
Chain: A
Length: 297 amino acids
Theoretical weight: 32.88 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02722 (Residues: 2-298; Coverage: 100%)
Gene names: AAC1, ANT1, SLC25A4
Sequence domains: Mitochondrial carrier protein
Structure domains: Mitochondrial carrier domain

Ligands and Environments

4 bound ligands:
Ligand CXT 1 x CXT
Ligand CDL 3 x CDL
Ligand LDM 2 x LDM
Ligand PC1 4 x PC1
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P21212
Unit cell:
a: 85.437Å b: 83.463Å c: 49.922Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.22 0.22 0.266

Quick links

Citations

145 review citations

Translocation of proteins into mitochondria.
Neupert et al. (2007)
144 more

127 mentions without citation

Alternative Splicing May Not Be the Key to Proteome Complexity.
Tress et al. (2017)
126 more