› 1olh

Solution NMR

HIGH-RESOLUTION SOLUTION STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF P53 BY MULTI-DIMENSIONAL NMR

Released:
DOI: 10.2210/pdb1olh/pdb
PDB entry 1olh coloured by chain, ensemble of 35 models, front view.
PDB entry 1olh coloured by chain, ensemble of 35 models, side view.
PDB entry 1olh coloured by chain, ensemble of 35 models, top view.
Source organism: Homo sapiens
Primary publication:
High-resolution structure of the oligomerization domain of p53 by multidimensional NMR.
Clore GM, Omichinski JG, Sakaguchi K, Zambrano N, Sakamoto H, Appella E, Gronenborn AM
Science 265 386-91 (1994)
PMID: 8023159

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138138 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular tumor antigen p53 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 42 amino acids
Theoretical weight: 4.95 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04637 (Residues: 319-360; Coverage: 11%)
Gene names: P53, TP53
Sequence domains: P53 tetramerisation motif
Structure domains: p53-like tetramerisation domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

37 review citations

Twenty years of p53 research: structural and functional aspects of the p53 protein.
May et al. (1999)
36 more

5 mentions without citation

p53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum Concept.
Uversky VN. (2016)
4 more