› 1ooi

X-ray diffraction
2.04Å resolution

Crystal structure of LUSH from Drosophila melanogaster at pH 6.5

Released:
DOI: 10.2210/pdb1ooi/pdb
PDB entry 1ooi coloured by chain, front view.
PDB entry 1ooi coloured by chain, side view.
PDB entry 1ooi coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster.
Kruse SW, Zhao R, Smith DP, Jones DN
Nat Struct Biol 10 694-700 (2003)
PMID: 12881720

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126416 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General odorant-binding protein lush Chain: X
Molecule details ›
Chain: X
Length: 124 amino acids
Theoretical weight: 14.22 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O02372 (Residues: 30-153; Coverage: 100%)
Gene names: CG8807, Obp76a, Obp76c, lush
Sequence domains: PBP/GOBP family
Structure domains: Pheromone/general odorant binding protein domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P61
Unit cell:
a: 55.37Å b: 55.37Å c: 66.946Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.195 0.247
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

22 review citations

Alcoholism: a systems approach from molecular physiology to addictive behavior.
Spanagel R. (2009)
21 more

6 mentions without citation

Structure of a specific alcohol-binding site defined by the odorant binding protein LUSH from Drosophila melanogaster.
Kruse et al. (2003)
5 more