› 1oqj

X-ray diffraction
1.55Å resolution

Crystal structure of the SAND domain from glucocorticoid modulatory element binding protein-1 (GMEB1)

Released:
DOI: 10.2210/pdb1oqj/pdb
PDB entry 1oqj coloured by chain, front view.
PDB entry 1oqj coloured by chain, side view.
PDB entry 1oqj coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions.
Surdo PL, Bottomley MJ, Sattler M, Scheffzek K
Mol Endocrinol 17 1283-95 (2003)
PMID: 12702733

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195346 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucocorticoid modulatory element-binding protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 97 amino acids
Theoretical weight: 11.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9Y692 (Residues: 89-182; Coverage: 16%)
Gene name: GMEB1
Sequence domains: SAND domain
Structure domains: SAND domain-like

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P212121
Unit cell:
a: 40.946Å b: 49.077Å c: 88.903Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.194 0.21
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

8 review citations

Aire.
Mathis et al. (2009)
7 more

3 mentions without citation

Prediction of structures of zinc-binding proteins through explicit modeling of metal coordination geometry.
Wang et al. (2010)
2 more