1oxo

X-ray diffraction
2.3Å resolution

ASPARTATE AMINOTRANSFERASE, H-ASP COMPLEX, OPEN CONFORMATION

Released:

Function and Biology Details

Reactions catalysed:
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate
(1a) L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-132574 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aspartate aminotransferase, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 401 amino acids
Theoretical weight: 44.99 KDa
Source organism: Gallus gallus
Expression system: unidentified
UniProt:
  • Canonical: P00508 (Residues: 23-423; Coverage: 95%)
Gene name: GOT2
Sequence domains: Aminotransferase class I and II
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P1
Unit cell:
a: 55.7Å b: 58.8Å c: 76Å
α: 85.2° β: 109.2° γ: 115.7°
Expression system: unidentified