› 1p5w

X-ray diffraction
3.3Å resolution

The structures of host range controlling regions of the capsids of canine and feline parvoviruses and mutants

Released:
DOI: 10.2210/pdb1p5w/pdb
PDB entry 1p5w coloured by chain, front view.
PDB entry 1p5w coloured by chain, side view.
PDB entry 1p5w coloured by chain, top view.
Source organism: Canine parvovirus
Primary publication:
Structures of host range-controlling regions of the capsids of canine and feline parvoviruses and mutants.
Govindasamy L, Hueffer K, Parrish CR, Agbandje-McKenna M
J Virol 77 12211-21 (2003)
PMID: 14581558

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero 120-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114361 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
Capsid protein VP1 Chain: A
Molecule details ›
Chain: A
Length: 548 amino acids
Theoretical weight: 61.61 KDa
Source organism: Canine parvovirus
Expression system: Felis catus
UniProt:
  • Canonical: P17455 (Residues: 180-727; Coverage: 75%)
Sequence domains: Parvovirus coat protein VP2
Structure domains: Parvovirus coat protein VP1/VP2
5'-D(P*(3DR)P*TP*AP*CP*CP*TP*CP*TP*TP*GP*C)-3' Chain: B
Molecule details ›
Chain: B
Length: 11 nucleotides
Theoretical weight: 3.15 KDa
Source organism: Canine parvovirus
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand MG 4 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P212121
Unit cell:
a: 372.417Å b: 373.017Å c: 377.083Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 0.202
Expression systems:
  • Felis catus
  • Not provided

Quick links

Citations

6 review citations

Cross-species virus transmission and the emergence of new epidemic diseases.
Parrish et al. (2008)
5 more

4 mentions without citation

Twenty-Five Years of Structural Parvovirology.
Mietzsch et al. (2019)
3 more