› 1p7b

X-ray diffraction
3.65Å resolution

Crystal structure of an inward rectifier potassium channel

Released:
DOI: 10.2210/pdb1p7b/pdb
PDB entry 1p7b coloured by chain, front view.
PDB entry 1p7b coloured by chain, side view.
PDB entry 1p7b coloured by chain, top view.
Source organism: Burkholderia pseudomallei
Primary publication:
Crystal structure of the potassium channel KirBac1.1 in the closed state.
Kuo A, Gulbis JM, Antcliff JF, Rahman T, Lowe ED, Zimmer J, Cuthbertson J, Ashcroft FM, Ezaki T, Doyle DA
Science 300 1922-6 (2003)
PMID: 12738871

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160729 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel Chains: A, B
Molecule details ›
Chains: A, B
Length: 333 amino acids
Theoretical weight: 37.18 KDa
Source organism: Burkholderia pseudomallei
Expression system: Escherichia coli
UniProt:
  • Canonical: P83698 (Residues: 1-333; Coverage: 100%)
Gene name: Y036_1623
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand K 4 x K
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: I222
Unit cell:
a: 92.84Å b: 105.62Å c: 258.63Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.297 0.295 0.329
Expression system: Escherichia coli

Quick links

Citations

125 review citations

Inwardly rectifying potassium channels: their structure, function, and physiological roles.
Hibino et al. (2010)
124 more

52 mentions without citation

Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins.
Bahar et al. (2010)
51 more