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Solution NMR

NMR SOLUTION STRUCTURE OF THE TETRAMERIC MINIMUM TRANSFORMING DOMAIN OF P53

Released:
DOI: 10.2210/pdb1pet/pdb
PDB entry 1pet coloured by chain, ensemble of 19 models, front view.
PDB entry 1pet coloured by chain, ensemble of 19 models, side view.
PDB entry 1pet coloured by chain, ensemble of 19 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the tetrameric minimum transforming domain of p53.
Lee W, Harvey TS, Yin Y, Yau P, Litchfield D, Arrowsmith CH
Nat Struct Biol 1 877-90 (1994)
PMID: 7773777

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138138 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cellular tumor antigen p53 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 31 amino acids
Theoretical weight: 3.77 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04637 (Residues: 325-355; Coverage: 8%)
Gene names: P53, TP53
Sequence domains: P53 tetramerisation motif

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

33 review citations

Structural biology of the tumor suppressor p53.
Joerger et al. (2008)
32 more

3 mentions without citation

Allosteric modulation of protein oligomerization: an emerging approach to drug design.
Gabizon et al. (2014)
2 more