› 1php

X-ray diffraction
1.65Å resolution

STRUCTURE OF THE ADP COMPLEX OF THE 3-PHOSPHOGLYCERATE KINASE FROM BACILLUS STEAROTHERMOPHILUS AT 1.65 ANGSTROMS

Released:
DOI: 10.2210/pdb1php/pdb
PDB entry 1php coloured by chain, front view.
PDB entry 1php coloured by chain, side view.
PDB entry 1php coloured by chain, top view.
Source organism: Geobacillus stearothermophilus
Primary publication:
Structure of the ADP complex of the 3-phosphoglycerate kinase from Bacillus stearothermophilus at 1.65 A.
Davies GJ, Gamblin SJ, Littlechild JA, Dauter Z, Wilson KS, Watson HC
Acta Crystallogr D Biol Crystallogr 50 202-9 (1994)
PMID: 15299460

Function and Biology Details

Reaction catalysed: 
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148477 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphoglycerate kinase Chain: A
Molecule details ›
Chain: A
Length: 394 amino acids
Theoretical weight: 42.79 KDa
Source organism: Geobacillus stearothermophilus
Expression system: Not provided
UniProt:
  • Canonical: P18912 (Residues: 1-394; Coverage: 100%)
Gene name: pgk
Sequence domains: Phosphoglycerate kinase
Structure domains: Phosphoglycerate kinase, N-terminal domain

Ligands and Environments

2 bound ligands:
Ligand MG 1 x MG
Ligand ADP 1 x ADP
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21
Unit cell:
a: 40.41Å b: 73.93Å c: 68.57Å
α: 90° β: 99.8° γ: 90°
R-values:
R R work R free
0.156 0.156 not available
Expression system: Not provided

Quick links

Citations

28 citation in other articles

Active site comparisons highlight structural similarities between myosin and other P-loop proteins.
Smith et al. (1996)
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23 mentions without citation

What lessons can be learned from studying the folding of homologous proteins?
Nickson et al. (2010)
22 more