› 1piq

X-ray diffraction
1.8Å resolution

CRYSTAL STRUCTURE OF GCN4-PIQ, A TRIMERIC COILED COIL WITH BURIED POLAR RESIDUES

Released:
DOI: 10.2210/pdb1piq/pdb
PDB entry 1piq coloured by chain, front view.
PDB entry 1piq coloured by chain, side view.
PDB entry 1piq coloured by chain, top view.
Source organism: Saccharomyces cerevisiae S288C
Primary publication:
Crystal structure of GCN4-pIQI, a trimeric coiled coil with buried polar residues.
Eckert DM, Malashkevich VN, Kim PS
J Mol Biol 284 859-65 (1998)
PMID: 9837709

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136531 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General control transcription factor GCN4 Chain: A
Molecule details ›
Chain: A
Length: 32 amino acids
Theoretical weight: 3.8 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Not provided
UniProt:
  • Canonical: P03069 (Residues: 249-279; Coverage: 11%)
Gene names: AAS101, AAS3, ARG9, GCN4, YEL009C
Sequence domains: Basic region leucine zipper

Ligands and Environments

1 bound ligand:
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P321
Unit cell:
a: 39.66Å b: 39.66Å c: 47.47Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.211 0.211 0.236
Expression system: Not provided

Quick links

Citations

6 review citations

Mechanisms of viral membrane fusion and its inhibition.
Eckert et al. (2001)
5 more

2 mentions without citation

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus.
Stewart-Jones et al. (2015)
1 more