Function and Biology Details
Reaction catalysed:
ATP + [receptor-protein] = ADP + [receptor-protein] phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
TGF-beta receptor type-2 (preferred)
PDBe Complex ID:
PDB-CPX-153364 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TGF-beta receptor type-2
Molecule details ›
Chain: A
Length: 122 amino acids
Theoretical weight: 13.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Transforming growth factor beta receptor 2 ectodomain
Structure domains: CD59
Length: 122 amino acids
Theoretical weight: 13.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P37173 (Residues: 38-159; Coverage: 22%)
Sequence domains: Transforming growth factor beta receptor 2 ectodomain
Structure domains: CD59
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
substructure distance geometry, full structure distance geometry-simulated annealing;
torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)
