› 1pog

Solution NMR

SOLUTION STRUCTURE OF THE OCT-1 POU-HOMEO DOMAIN DETERMINED BY NMR AND RESTRAINED MOLECULAR DYNAMICS

Released:
DOI: 10.2210/pdb1pog/pdb
PDB entry 1pog coloured by chain, ensemble of 13 models, front view.
PDB entry 1pog coloured by chain, ensemble of 13 models, side view.
PDB entry 1pog coloured by chain, ensemble of 13 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the Oct-1 POU homeodomain determined by NMR and restrained molecular dynamics.
Cox M, van Tilborg PJ, de Laat W, Boelens R, van Leeuwen HC, van der Vliet PC, Kaptein R
J Biomol NMR 6 23-32 (1995)
PMID: 7663141

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147106 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
POU domain, class 2, transcription factor 1 Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 8.19 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P14859 (Residues: 378-438; Coverage: 8%)
Gene names: OCT1, OTF1, POU2F1
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The virtuoso of versatility: POU proteins that flex to fit.
Phillips et al. (2000)
3 more

3 mentions without citation

Structural basis for inhibition of homologous recombination by the RecX protein.
Ragone et al. (2008)
2 more