› 1ps2

Solution NMR

HIGH RESOLUTION NMR SOLUTION STRUCTURE OF HUMAN PS2, 19 STRUCTURES

Released:
DOI: 10.2210/pdb1ps2/pdb
PDB entry 1ps2 coloured by chain, ensemble of 19 models, front view.
PDB entry 1ps2 coloured by chain, ensemble of 19 models, side view.
PDB entry 1ps2 coloured by chain, ensemble of 19 models, top view.
Source organism: Homo sapiens
Primary publication:
High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein.
Polshakov VI, Williams MA, Gargaro AR, Frenkiel TA, Westley BR, Chadwick MP, May FE, Feeney J
J Mol Biol 267 418-32 (1997)
PMID: 9096235

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137453 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trefoil factor 1 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 6.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04155 (Residues: 25-84; Coverage: 100%)
Gene names: BCEI, PS2, TFF1
Sequence domains: Trefoil (P-type) domain
Structure domains: Spasmolytic Protein, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Trefoil factors: initiators of mucosal healing.
Taupin et al. (2003)
7 more

3 mentions without citation

Utilizing NMR to study the structure of growth-inhibitory proteins.
Marassi F. (2003)
2 more