1pwa

X-ray diffraction
1.3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-132012 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor 19 Chain: A
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 18.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95750 (Residues: 39-196; Coverage: 82%)
Gene names: FGF19, UNQ334/PRO533
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.2
Spacegroup: R32
Unit cell:
a: 67.573Å b: 67.573Å c: 193.374Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.181 0.18 0.195
Expression system: Escherichia coli