› 1q0g

X-ray diffraction
1.6Å resolution

Crystal structure of Ni-containing superoxide dismutase with Ni-ligation corresponding to the state after full x-ray-induced reduction

Released:
DOI: 10.2210/pdb1q0g/pdb
PDB entry 1q0g coloured by chain, front view.
PDB entry 1q0g coloured by chain, side view.
PDB entry 1q0g coloured by chain, top view.
Source organism: Streptomyces seoulensis
Primary publication:
Crystal structure of nickel-containing superoxide dismutase reveals another type of active site.
Wuerges J, Lee JW, Yim YI, Yim HS, Kang SO, Djinovic Carugo K
Proc Natl Acad Sci U S A 101 8569-74 (2004)
PMID: 15173586

Function and Biology Details

Reaction catalysed: 
2 superoxide + 2 H(+) = O(2) + H(2)O(2)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160453 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Superoxide dismutase [Ni] Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 117 amino acids
Theoretical weight: 13.21 KDa
Source organism: Streptomyces seoulensis
UniProt:
  • Canonical: P80734 (Residues: 15-131; Coverage: 89%)
Gene name: sodN
Sequence domains: Nickel-containing superoxide dismutase
Structure domains: Nickel-containing superoxide dismutase

Ligands and Environments

2 bound ligands:
Ligand NI 12 x NI
Ligand SO4 16 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P212121
Unit cell:
a: 112.264Å b: 113.811Å c: 128.603Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.184 0.202

Quick links

Citations

23 review citations

Superoxide dismutases: ancient enzymes and new insights.
Miller AF. (2012)
22 more

4 mentions without citation

Superoxide dismutases and superoxide reductases.
Sheng et al. (2014)
3 more