› 1q2z

Solution NMR

The 3D solution structure of the C-terminal region of Ku86

Released:
DOI: 10.2210/pdb1q2z/pdb
PDB entry 1q2z coloured by chain, ensemble of 20 models, front view.
PDB entry 1q2z coloured by chain, ensemble of 20 models, side view.
PDB entry 1q2z coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The 3D solution structure of the C-terminal region of Ku86 (Ku86CTR).
Harris R, Esposito D, Sankar A, Maman JD, Hinks JA, Pearl LH, Driscoll PC
J Mol Biol 335 573-82 (2004)
PMID: 14672664

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146431 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
X-ray repair cross-complementing protein 5 Chain: A
Molecule details ›
Chain: A
Length: 120 amino acids
Theoretical weight: 13.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13010 (Residues: 590-709; Coverage: 16%)
Gene names: G22P2, XRCC5
Sequence domains: Ku C terminal domain like
Structure domains: Ku, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

14 review citations

Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining.
Mahaney et al. (2009)
13 more

4 mentions without citation

Structural model of full-length human Ku70-Ku80 heterodimer and its recognition of DNA and DNA-PKcs.
Rivera-Calzada et al. (2007)
3 more