› 1q3l

X-ray diffraction
1.64Å resolution

Chromodomain Of HP1 Complexed With Histone H3 Tail Containing monomethyllysine 9.

Released:
DOI: 10.2210/pdb1q3l/pdb
PDB entry 1q3l coloured by chain, front view.
PDB entry 1q3l coloured by chain, side view.
PDB entry 1q3l coloured by chain, top view.
Source organisms:
Entry authors: Jacobs SA, Khorasanizadeh S

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138596 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Heterochromatin protein 1 Chain: A
Molecule details ›
Chain: A
Length: 69 amino acids
Theoretical weight: 8.59 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P05205 (Residues: 17-76; Coverage: 29%)
Gene names: CG8409, HP1, HP1a, Su(var)2-5, Su(var)205
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
Histone H3.1 Chain: P
Molecule details ›
Chain: P
Length: 16 amino acids
Theoretical weight: 1.74 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P68431 (Residues: 2-17; Coverage: 12%)
Gene names: H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, H3C8, H3FA, H3FB, H3FC HIST1H3C, H3FD, H3FF, H3FH, H3FI, H3FJ, H3FK, H3FL, HIST1H3A, HIST1H3B, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MLZ 1 x MLZ

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2221
Unit cell:
a: 33.809Å b: 76.828Å c: 75.625Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.222 0.241
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided

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