› 1qc0

X-ray diffraction
1.55Å resolution

CRYSTAL STRUCTURE OF A 19 BASE PAIR COPY CONTROL RELATED RNA DUPLEX

Released:
DOI: 10.2210/pdb1qc0/pdb
PDB entry 1qc0 coloured by chain, front view.
PDB entry 1qc0 coloured by chain, side view.
PDB entry 1qc0 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystal structures of two plasmid copy control related RNA duplexes: An 18 base pair duplex at 1.20 A resolution and a 19 base pair duplex at 1.55 A resolution.
Klosterman PS, Shah SA, Steitz TA
Biochemistry 38 14784-92 (1999)
PMID: 10555960

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
hetero tetramer
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-219684 (preferred)
Entry contents:
4 distinct RNA molecules
Macromolecules (4 distinct):
5'-R(*UP*AP*GP*CP*GP*GP*UP*GP*C)-3' Chain: A
Molecule details ›
Chain: A
Length: 9 nucleotides
Theoretical weight: 2.89 KDa
Source organism: Escherichia coli
Expression system: Not provided
5'-R(GP*CP*AP*CP*CP*GP*CP*UP*AP*C)-3' Chain: B
Molecule details ›
Chain: B
Length: 10 nucleotides
Theoretical weight: 3.14 KDa
Source organism: Escherichia coli
Expression system: Not provided
5'-R(*GP*CP*AP*CP*CP*GP*UP*UP*GP*GP*UP*AP*GP*CP*GP*GP*UP*GP*C)-3' Chain: C
Molecule details ›
Chain: C
Length: 19 nucleotides
Theoretical weight: 6.13 KDa
Source organism: Escherichia coli
Expression system: Not provided
5'-R(*GP*CP*AP*CP*CP*GP*CP*UP*AP*CP*CP*AP*AP*CP*GP*GP*UP*GP*C)-3' Chain: D
Molecule details ›
Chain: D
Length: 19 nucleotides
Theoretical weight: 6.05 KDa
Source organism: Escherichia coli
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand NH4 7 x NH4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1, RIGAKU RU300
Spacegroup: R32
Unit cell:
a: 43.682Å b: 43.682Å c: 447.021Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.153 0.15 0.214
Expression system: Not provided

Quick links

Citations

5 review citations

Structure and function of Toll receptors and their ligands.
Gay et al. (2007)
4 more

19 mentions without citation

Sequence- and target-independent angiogenesis suppression by siRNA via TLR3.
Kleinman et al. (2008)
18 more