Function and Biology Details
Reaction catalysed:
(1a) L-glutamine + H(2)O = L-glutamate + NH(3)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Anthranilate synthase component I-like
- Anthranilate synthase/para-aminobenzoate synthase like domain
- Class I glutamine amidotransferase-like
- ADC synthase
- Glutamine amidotransferase
- Chorismate-utilising enzyme, C-terminal
- Anthranilate synthase component I, archaeal type
- Anthranilate synthase component I, N-terminal
Structure domains:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Anthranilate synthase (preferred)
PDBe Complex ID:
PDB-CPX-170291 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Anthranilate synthase component 1
Molecule details ›
Chain: A
Length: 422 amino acids
Theoretical weight: 47.78 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains: Anthranilate synthase
Length: 422 amino acids
Theoretical weight: 47.78 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q06128 (Residues: 1-421; Coverage: 100%)
Sequence domains:
Structure domains: Anthranilate synthase
Anthranilate synthase component 2
Molecule details ›
Chain: B
Length: 195 amino acids
Theoretical weight: 21.94 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
Sequence domains: Glutamine amidotransferase class-I
Structure domains: Rossmann fold
Length: 195 amino acids
Theoretical weight: 21.94 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
- Canonical: Q06129 (Residues: 1-195; Coverage: 100%)
Sequence domains: Glutamine amidotransferase class-I
Structure domains: Rossmann fold
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup:
P6322
Expression system: Escherichia coli
