Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Tyrosine-protein kinase BTK (preferred)
PDBe Complex ID:
PDB-CPX-170299 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase BTK
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Length: 58 amino acids
Theoretical weight: 6.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
Q06187 (Residues: 216-273; Coverage: 9%)
Sequence domains: SH3 domain
Structure domains: SH3 Domains
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
simulated annealing
Expression system: Escherichia coli BL21
