Function and Biology Details
Reaction catalysed:
Preferential cleavage: Lys-|-Xaa > Arg-|-Xaa, higher selectivity than trypsin. Converts fibrin into soluble products.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Angiostatin (preferred)
PDBe Complex ID:
PDB-CPX-133230 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plasmin light chain B
Molecule details ›
Chains: A, B, C, D
Length: 246 amino acids
Theoretical weight: 27.02 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 246 amino acids
Theoretical weight: 27.02 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical:
P00747 (Residues: 565-810; Coverage: 31%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X12B
Spacegroup:
P21
Expression system: Not provided
