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› 1qs3

Solution NMR

NMR SOLUTION CONFORMATION OF AN ANTITOXIC ANALOG OF ALPHA-CONOTOXIN GI

Released:
DOI: 10.2210/pdb1qs3/pdb
PDB entry 1qs3 coloured by chain, ensemble of 30 models, front view.
PDB entry 1qs3 coloured by chain, ensemble of 30 models, side view.
PDB entry 1qs3 coloured by chain, ensemble of 30 models, top view.
Source organism: Conus geographus
Primary publication:
NMR solution conformation of an antitoxic analogue of alpha-conotoxin GI: identification of a common nicotinic acetylcholine receptor alpha 1-subunit binding surface for small ligands and alpha-conotoxins.
Mok KH, Han KH
Biochemistry 38 11895-904 (1999)
PMID: 10508392

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144116 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-conotoxin GIA Chain: A
Molecule details ›
Chain: A
Length: 12 amino acids
Theoretical weight: 1.18 KDa
Source organism: Conus geographus
Expression system: Not provided
UniProt:
  • Canonical: P0DQR7 (Residues: 2-12; Coverage: 73%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS
Expression system: Not provided

Quick links

Citations

2 review citations

Structure-activity relationships of alpha-conotoxins targeting neuronal nicotinic acetylcholine receptors.
Millard et al. (2004)
1 more

1 mention without citation

Generalized pattern search algorithm for Peptide structure prediction.
Nicosia et al. (2008)