Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assemblies composition:
Assembly name:
PDBe Complex ID:
PDB-CPX-147430 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
N-VEGF
Molecule details ›
Chains: R, S, V, W
Length: 102 amino acids
Theoretical weight: 11.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: VEGF heparin-binding domain
Structure domains: Cystine-knot cytokines
Length: 102 amino acids
Theoretical weight: 11.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P15692 (Residues: 214-315; Coverage: 26%)
Sequence domains: VEGF heparin-binding domain
Structure domains: Cystine-knot cytokines
Vascular endothelial growth factor receptor 1
Molecule details ›
Chains: T, U, X, Y
Length: 101 amino acids
Theoretical weight: 11.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Vascular endothelial growth factor receptor 1-like, Ig-like domain
Structure domains: Immunoglobulins
Length: 101 amino acids
Theoretical weight: 11.54 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P17948 (Residues: 129-229; Coverage: 8%)
Sequence domains: Vascular endothelial growth factor receptor 1-like, Ig-like domain
Structure domains: Immunoglobulins
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU
Spacegroup:
C2
Expression system: Escherichia coli
