EC 3.1.21.2: Deoxyribonuclease IV
Reaction catalysed:
Endonucleolytic cleavage to 5'-phosphooligonucleotide end-products
Systematic name:
-
Alternative Name(s):
- DNA-adenine-transferase
- Deoxriboendonuclease
- Deoxyribonuclease IV (phage T4-induced)
- E. coli endonuclease IV
- Endodeoxyribonuclease
- Endodeoxyribonuclease IV (phage T(4)-induced)
- Endodeoxyribonuclease IV (phage T4-induced)
- Endonuclease II
- Endonuclease IV
- Escherichia coli endonuclease II
- Nfo (gene name)
- Redoxyendonuclease
GO terms
Biochemical function:
- metal ion binding
- phosphatase activity
- hydrolase activity
- deoxyribonuclease IV (phage-T4-induced) activity
- 3'-5'-DNA exonuclease activity
- zinc ion binding
- phosphoric diester hydrolase activity
- endonuclease activity
- nuclease activity
- DNA-(apurinic or apyrimidinic site) endonuclease activity
- DNA binding
Protein family (Pfam)![The deposited structure of PDB entry 1qum contains 1 copy of Pfam domain PF01261 (Xylose isomerase-like TIM barrel) in Endonuclease 4. Showing 1 copy in chain D [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/1qum_4_A_Pfam_PF01261_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1qum</span> contains 1 copy of Pfam domain <span class='highlight'>PF01261 (Xylose isomerase-like TIM barrel)</span> in <span class='highlight'>Endonuclease 4</span>. Showing 1 copy in chain <span class='highlight'>D [auth A]</span>.")
InterPro annotations
CATH domain![The deposited structure of PDB entry 1qum contains 1 copy of CATH domain 3.20.20.150 (TIM Barrel) in Endonuclease 4. Showing 1 copy in chain D [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/1qum_4_A_CATH_3.20.20.150_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1qum</span> contains 1 copy of CATH domain <span class='highlight'>3.20.20.150 (TIM Barrel)</span> in <span class='highlight'>Endonuclease 4</span>. Showing 1 copy in chain <span class='highlight'>D [auth A]</span>.")
SCOP annotation![The deposited structure of PDB entry 1qum contains 1 copy of SCOP domain 51659 (Endonuclease IV) in Endonuclease 4. Showing 1 copy in chain D [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/1qum_4_A_SCOP_51659_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1qum</span> contains 1 copy of SCOP domain <span class='highlight'>51659 (Endonuclease IV)</span> in <span class='highlight'>Endonuclease 4</span>. Showing 1 copy in chain <span class='highlight'>D [auth A]</span>.")