› 1qvv

X-ray diffraction
2.35Å resolution

Crystal structure of the S. cerevisiae YDR533c protein

Released:
DOI: 10.2210/pdb1qvv/pdb
PDB entry 1qvv coloured by chain, front view.
PDB entry 1qvv coloured by chain, side view.
PDB entry 1qvv coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Crystal structure of the YDR533c S. cerevisiae protein, a class II member of the Hsp31 family.
Graille M, Quevillon-Cheruel S, Leulliot N, Zhou CZ, Li de la Sierra Gallay I, Jacquamet L, Ferrer JL, Liger D, Poupon A, Janin J, van Tilbeurgh H
Structure 12 839-47 (2004)
PMID: 15130476

Function and Biology Details

Reaction catalysed: 
(R)-lactate = methylglyoxal + H(2)O
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170028 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione-independent glyoxalase HSP31 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 237 amino acids
Theoretical weight: 25.78 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q04432 (Residues: 1-237; Coverage: 100%)
Gene names: D9719.36, HSP31, YDR533C
Sequence domains: DJ-1/PfpI family
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
1 modified residue:
Ligand CME 4 x CME

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P212121
Unit cell:
a: 67.019Å b: 93.636Å c: 151.738Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.228 0.283
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Lessons from structural genomics.
Terwilliger et al. (2009)
1 more

2 mentions without citation

PAR-3D: a server to predict protein active site residues.
Goyal et al. (2007)
1 more