› 1r5d

X-ray diffraction
2.5Å resolution

X-ray structure of bovine seminal ribonuclease swapping dimer from a new crystal form

Released:
DOI: 10.2210/pdb1r5d/pdb
PDB entry 1r5d coloured by chain, front view.
PDB entry 1r5d coloured by chain, side view.
PDB entry 1r5d coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Population shift vs induced fit: the case of bovine seminal ribonuclease swapping dimer.
Merlino A, Vitagliano L, Sica F, Zagari A, Mazzarella L
Biopolymers 73 689-95 (2004)
PMID: 15048772

Function and Biology Details

Reaction catalysed: 
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132818 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Seminal ribonuclease Chains: A, B
Molecule details ›
Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.63 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00669 (Residues: 27-150; Coverage: 100%)
Gene name: SRN
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ENRAF-NONIUS FR591
Spacegroup: P212121
Unit cell:
a: 49.57Å b: 60.22Å c: 83.44Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.185 0.255

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Citations

14 citation in other articles

Protein flexibility using constraints from molecular dynamics simulations.
Mamonova et al. (2005)
13 more