› 1r8n

X-ray diffraction
1.75Å resolution

The Crystal Structure of the Kunitz (STI) Type Inhibitor from Seeds of Delonix regia

Released:
DOI: 10.2210/pdb1r8n/pdb
PDB entry 1r8n coloured by chain, front view.
PDB entry 1r8n coloured by chain, side view.
PDB entry 1r8n coloured by chain, top view.
Source organism: Delonix regia
Primary publication:
Crystal structure of the Kunitz (STI)-type inhibitor from Delonix regia seeds.
Krauchenco S, Pando SC, Marangoni S, Polikarpov I
Biochem Biophys Res Commun 312 1303-8 (2003)
PMID: 14652016

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160716 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kunitz-type serine protease inhibitor DrTI Chain: A
Molecule details ›
Chain: A
Length: 185 amino acids
Theoretical weight: 20.2 KDa
Source organism: Delonix regia
UniProt:
  • Canonical: P83667 (Residues: 1-185; Coverage: 100%)
Sequence domains: Trypsin and protease inhibitor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: P212121
Unit cell:
a: 32.125Å b: 67.249Å c: 72.061Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.215 0.252

Quick links

Citations

20 citation in other articles

A Kunitz trypsin inhibitor from chickpea (Cicer arietinum L.) that exerts anti-metabolic effect on podborer (Helicoverpa armigera) larvae.
Srinivasan et al. (2005)
19 more

11 mentions without citation

The ternary structure of the double-headed arrowhead protease inhibitor API-A complexed with two trypsins reveals a novel reactive site conformation.
Bao et al. (2009)
10 more