› 1rbn

X-ray diffraction
2.1Å resolution

THE STRUCTURE OF RIBONUCLEASE A DERIVATIVE II AT 2.1 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb1rbn/pdb
PDB entry 1rbn coloured by chain, front view.
PDB entry 1rbn coloured by chain, side view.
PDB entry 1rbn coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structure of ribonuclease A derivative II at 2.1-A resolution.
Boqué L, Gràcia Coll M, Vilanova M, Cuchillo CM, Fita I
J Biol Chem 269 19707-12 (1994)
PMID: 8051049

Function and Biology Details

Reaction catalysed: 
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158390 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease pancreatic Chain: A
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

1 bound ligand:
Ligand P5P 1 x P5P
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 75.73Å b: 57.85Å c: 53.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.166 0.166 not available
Expression system: Not provided

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Citations

1 citations in other articles

Interaction of human pancreatic ribonuclease with human ribonuclease inhibitor. Generation of inhibitor-resistant cytotoxic variants.
Gaur et al. (2001)

2 mentions without citation

NMR of hydrogen bonding in cold-shock protein A and an analysis of the influence of crystallographic resolution on comparisons of hydrogen bond lengths.
Alexandrescu et al. (2001)
1 more