1s31

X-ray diffraction
2.7Å resolution

Crystal Structure Analysis of the human Tub protein (isoform a) spanning residues 289 through 561

Released:
Source organism: Homo sapiens
Entry authors: Boutboul S, Carroll KJ, Basdevant A, Gomez C, Nandrot E, Clement K, Shapiro L, Abitbol M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-156237 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tubby protein homolog Chain: A
Molecule details ›
Chain: A
Length: 273 amino acids
Theoretical weight: 30.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P50607 (Residues: 234-506; Coverage: 54%)
Gene name: TUB
Sequence domains: Tub family
Structure domains: Tubby Protein; Chain A

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 32-ID
Spacegroup: I23
Unit cell:
a: 149.981Å b: 149.981Å c: 149.981Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.181 0.226
Expression system: Escherichia coli BL21(DE3)