› 1s4g

Solution NMR

Somatomedin-B Domain of human plasma vitronectin.

Released:
DOI: 10.2210/pdb1s4g/pdb
PDB entry 1s4g coloured by chain, ensemble of 20 models, front view.
PDB entry 1s4g coloured by chain, ensemble of 20 models, side view.
PDB entry 1s4g coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The solution structure of the N-terminal domain of human vitronectin: proximal sites that regulate fibrinolysis and cell migration.
Mayasundari A, Whittemore NA, Serpersu EH, Peterson CB
J Biol Chem 279 29359-66 (2004)
PMID: 15123712

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137317 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Somatomedin-B Chain: A
Molecule details ›
Chain: A
Length: 51 amino acids
Theoretical weight: 5.82 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P04004 (Residues: 20-70; Coverage: 11%)
Gene name: VTN
Sequence domains: Somatomedin B domain

Ligands and Environments

1 bound ligand:
Ligand OH 1 x OH
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing

Quick links

Citations

4 review citations

Allosteric disulfide bonds in thrombosis and thrombolysis.
Chen et al. (2006)
3 more

2 mentions without citation

Functional structure of the somatomedin B domain of vitronectin.
Zhou A. (2007)
1 more