› 1smb

X-ray diffraction
1.55Å resolution

Crystal Structure of Golgi-Associated PR-1 protein

Released:
DOI: 10.2210/pdb1smb/pdb
PDB entry 1smb coloured by chain, front view.
PDB entry 1smb coloured by chain, side view.
PDB entry 1smb coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural analysis of the human Golgi-associated plant pathogenesis related protein GAPR-1 implicates dimerization as a regulatory mechanism.
Serrano RL, Kuhn A, Hendricks A, Helms JB, Sinning I, Groves MR
J Mol Biol 339 173-83 (2004)
PMID: 15123429

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190611 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Golgi-associated plant pathogenesis-related protein 1 Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 17.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H4G4 (Residues: 1-154; Coverage: 100%)
Gene names: C9orf19, GAPR1, GLIPR2
Sequence domains: Cysteine-rich secretory protein family
Structure domains: CAP

Ligands and Environments

No bound ligands
1 modified residue:
Ligand OCS 2 x OCS

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P3121
Unit cell:
a: 73.662Å b: 73.662Å c: 63.363Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.188 0.188 0.197
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Significance of inducible defense-related proteins in infected plants.
van Loon et al. (2006)
2 more

17 mentions without citation

Regulation of Functional Protein Aggregation by Multiple Factors: Implications for the Amyloidogenic Behavior of the CAP Superfamily Proteins.
Sheng et al. (2020)
16 more