› 1srz

Solution NMR

Solution structure of the second complement control protein (CCP) module of the GABA(B)R1a receptor, Pro-119 trans conformer

Released:
DOI: 10.2210/pdb1srz/pdb
PDB entry 1srz coloured by chain, ensemble of 24 models, front view.
PDB entry 1srz coloured by chain, ensemble of 24 models, side view.
PDB entry 1srz coloured by chain, ensemble of 24 models, top view.
Source organism: Rattus norvegicus
Primary publication:
Structural analysis of the complement control protein (CCP) modules of GABA(B) receptor 1a: only one of the two CCP modules is compactly folded.
Blein S, Ginham R, Uhrin D, Smith BO, Soares DC, Veltel S, McIlhinney RA, White JH, Barlow PN
J Biol Chem 279 48292-306 (2004)
PMID: 15304491

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195531 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gamma-aminobutyric acid type B receptor subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 68 amino acids
Theoretical weight: 7.49 KDa
Source organism: Rattus norvegicus
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q9Z0U4 (Residues: 96-159; Coverage: 7%)
Gene name: Gabbr1
Sequence domains: Sushi repeat (SCR repeat)
Structure domains: Complement Module, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, molecular dynamics
Expression system: Komagataella pastoris

Quick links

Citations

18 review citations

Regulation of neuronal GABA(B) receptor functions by subunit composition.
Gassmann et al. (2012)
17 more

4 mentions without citation

Structural biology of GABAB receptor.
Frangaj et al. (2018)
3 more