› 1su4

X-ray diffraction
2.4Å resolution

Crystal structure of calcium ATPase with two bound calcium ions

Released:
DOI: 10.2210/pdb1su4/pdb
PDB entry 1su4 coloured by chain, front view.
PDB entry 1su4 coloured by chain, side view.
PDB entry 1su4 coloured by chain, top view.
Source organism: Oryctolagus cuniculus
Primary publication:
Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 A resolution.
Toyoshima C, Nakasako M, Nomura H, Ogawa H
Nature 405 647-55 (2000)
PMID: 10864315

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137501 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand NA 1 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL41XU, SPRING-8 BEAMLINE BL44B2
Spacegroup: C2
Unit cell:
a: 165.89Å b: 64.34Å c: 147.14Å
α: 90° β: 98.08° γ: 90°
R-values:
R R work R free
0.251 0.246 0.283

Quick links

Citations

219 review citations

Biochemistry of Na,K-ATPase.
Kaplan JH. (2002)
218 more

101 mentions without citation

Lipid bilayer regulation of membrane protein function: gramicidin channels as molecular force probes.
Lundbaek et al. (2010)
100 more