› 1svv

X-ray diffraction
2.1Å resolution

Initial Stuctural Analysis of Leishmania major Threonine Aldolase

Released:
DOI: 10.2210/pdb1svv/pdb
PDB entry 1svv coloured by chain, front view.
PDB entry 1svv coloured by chain, side view.
PDB entry 1svv coloured by chain, top view.
Source organism: Leishmania major
Entry authors: Hol WGJ, Robien MA, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Reaction catalysed: 
L-threonine = glycine + acetaldehyde
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123136 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aromatic amino acid beta-eliminating lyase/threonine aldolase domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 359 amino acids
Theoretical weight: 39.93 KDa
Source organism: Leishmania major
Expression system: Escherichia coli
UniProt:
  • Canonical: E9AC39 (Residues: 1-359; Coverage: 100%)
Gene name: LMJF_01_0480
Sequence domains: Beta-eliminating lyase
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand UNL 2 x UNL
1 modified residue:
Ligand MSE 26 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P43212
Unit cell:
a: 119.094Å b: 119.094Å c: 129.597Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.198 0.23
Expression system: Escherichia coli

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