› 1sw8

Solution NMR

Solution structure of the N-terminal domain of Human N60D calmodulin refined with paramagnetism based strategy

Released:
DOI: 10.2210/pdb1sw8/pdb
PDB entry 1sw8 coloured by chain, ensemble of 20 models, front view.
PDB entry 1sw8 coloured by chain, ensemble of 20 models, side view.
PDB entry 1sw8 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Experimentally exploring the conformational space sampled by domain reorientation in calmodulin.
Bertini I, Del Bianco C, Gelis I, Katsaros N, Luchinat C, Parigi G, Peana M, Provenzani A, Zoroddu MA
Proc Natl Acad Sci U S A 101 6841-6 (2004)
PMID: 15100408

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143908 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin-1 Chain: A
Molecule details ›
Chain: A
Length: 79 amino acids
Theoretical weight: 8.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP23 (Residues: 2-80; Coverage: 53%)
Gene names: CALM, CALM1, CAM, CAM1
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

26 review citations

Theory, practice, and applications of paramagnetic relaxation enhancement for the characterization of transient low-population states of biological macromolecules and their complexes.
Clore et al. (2009)
25 more

2 mentions without citation

Experimentally exploring the conformational space sampled by domain reorientation in calmodulin.
Bertini et al. (2004)
1 more