› 1syr

X-ray diffraction
2.95Å resolution

Initial Structural Analysis of Plasmodium falciparum thioredoxin

Released:
DOI: 10.2210/pdb1syr/pdb
PDB entry 1syr coloured by chain, front view.
PDB entry 1syr coloured by chain, side view.
PDB entry 1syr coloured by chain, top view.
Source organism: Plasmodium falciparum 3D7
Entry authors: Robien MA, Hol WGJ, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181608 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin 1 Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 112 amino acids
Theoretical weight: 12.76 KDa
Source organism: Plasmodium falciparum 3D7
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7KQL8 (Residues: 1-104; Coverage: 100%)
Gene names: PF14_0545, PF3D7_1457200, TRX1
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: C2221
Unit cell:
a: 108.189Å b: 201.308Å c: 200.504Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.197 0.236
Expression system: Escherichia coli

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