1sz0

X-ray diffraction
2.1Å resolution

N-terminal 3 domains of CI-MPR bound to mannose 6-phosphate

Released:
Source organism: Bos taurus

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-139952 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Cation-independent mannose-6-phosphate receptor Chains: A, B
Molecule details ›
Chains: A, B
Length: 432 amino acids
Theoretical weight: 47.62 KDa
Source organism: Bos taurus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P08169 (Residues: 45-476; Coverage: 18%)
Gene names: IGF2R, M6P
Sequence domains: Cation-independent mannose-6-phosphate receptor repeat
Structure domains: Mannose-6-phosphate receptor binding domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, NDG
Carbohydrate polymer : NEW Components: NAG
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 61.1Å b: 86.5Å c: 84.8Å
α: 90° β: 109.57° γ: 90°
R-values:
R R work R free
0.238 0.238 0.287
Expression system: Trichoplusia ni