Assemblies
Assembly Name:
NAD-dependent protein deacetylase HST2 and Histone H4
Multimeric state:
hetero dimer
Accessible surface area:
13553.36 Å2
Buried surface area:
3121.47 Å2
Dissociation area:
687.06
Å2
Dissociation energy (ΔGdiss):
4.7
kcal/mol
Dissociation entropy (TΔSdiss):
7.19
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-135457
Assembly Name:
NAD-dependent protein deacetylase HST2 and Histone H4
Multimeric state:
hetero tetramer
Accessible surface area:
25001.5 Å2
Buried surface area:
8332.4 Å2
Dissociation area:
1,044.7
Å2
Dissociation energy (ΔGdiss):
5.85
kcal/mol
Dissociation entropy (TΔSdiss):
13.62
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-135464
Macromolecules
Chain: A
Length: 297 amino acids
Theoretical weight: 33.48 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
Pfam: Sir2 family
InterPro:
SCOP: Sir2 family of transcriptional regulators
Length: 297 amino acids
Theoretical weight: 33.48 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
- Canonical:
P53686 (Residues: 1-294; Coverage: 82%)
Pfam: Sir2 family
InterPro:
- Sirtuin, class I
- Sirtuin family, catalytic core domain
- DHS-like NAD/FAD-binding domain superfamily
- Sirtuin family
- Sirtuin, catalytic core small domain superfamily
SCOP: Sir2 family of transcriptional regulators
