Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114625 (preferred)
Entry contents:
3 distinct polypeptide molecules
2 distinct DNA molecules
2 distinct DNA molecules
Macromolecules (5 distinct):
Interferon regulatory factor 3
Molecule details ›
Chains: A, B
Length: 112 amino acids
Theoretical weight: 13.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Interferon regulatory factor transcription factor
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Length: 112 amino acids
Theoretical weight: 13.06 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q14653 (Residues: 1-112; Coverage: 26%)
Sequence domains: Interferon regulatory factor transcription factor
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Transcription factor Jun
Molecule details ›
Chain: C
Length: 62 amino acids
Theoretical weight: 7.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: bZIP transcription factor
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 62 amino acids
Theoretical weight: 7.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P05412 (Residues: 254-314; Coverage: 18%)
Sequence domains: bZIP transcription factor
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Cyclic AMP-dependent transcription factor ATF-2
Molecule details ›
Chain: D
Length: 61 amino acids
Theoretical weight: 7.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: bZIP transcription factor
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 61 amino acids
Theoretical weight: 7.13 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P15336 (Residues: 354-414; Coverage: 12%)
Sequence domains: bZIP transcription factor
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
CHESS BEAMLINE F1
Spacegroup:
C2
Expression system: Escherichia coli BL21(DE3)
