Function and Biology Details
Reaction catalysed:
GTP = 3',5'-cyclic GMP + diphosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
ANPR-A receptor complex and Atriopeptin-1 (preferred)
PDBe Complex ID:
PDB-CPX-134083 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
Atrial natriuretic peptide receptor 1
Molecule details ›
Chains: A, B
Length: 435 amino acids
Theoretical weight: 48.43 KDa
Source organism: Rattus norvegicus
Expression system: Cricetulus griseus
UniProt:
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold
Length: 435 amino acids
Theoretical weight: 48.43 KDa
Source organism: Rattus norvegicus
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P18910 (Residues: 29-463; Coverage: 42%)
Sequence domains: Receptor family ligand binding region
Structure domains: Rossmann fold
Atriopeptin-1
Molecule details ›
Chain: H
Length: 21 amino acids
Theoretical weight: 2.22 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
Sequence domains: Atrial natriuretic peptide
Length: 21 amino acids
Theoretical weight: 2.22 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
- Canonical: P01161 (Residues: 129-149; Coverage: 16%)
Sequence domains: Atrial natriuretic peptide
