Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
- Immunoglobulin C1-set
- MHC class II, beta chain, N-terminal
- Immunoglobulin/major histocompatibility complex, conserved site
- Immunoglobulin-like domain
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like fold
- MHC class II, alpha chain, N-terminal
- MHC class II, alpha/beta chain, N-terminal
1 more domain
Structure domains:
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-135335 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class II histocompatibility antigen, DR alpha chain
Molecule details ›
Chains: A, D
Length: 180 amino acids
Theoretical weight: 20.97 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains:
Structure domains:
Length: 180 amino acids
Theoretical weight: 20.97 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical:
P01903 (Residues: 27-206; Coverage: 79%)
Sequence domains:
Structure domains:
HLA class II histocompatibility antigen, DRB1 beta chain
Molecule details ›
Chains: B, E
Length: 190 amino acids
Theoretical weight: 22.08 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
Sequence domains:
Structure domains:
Length: 190 amino acids
Theoretical weight: 22.08 KDa
Source organism: Homo sapiens
Expression system: Drosophila melanogaster
UniProt:
- Canonical: P01911 (Residues: 30-219; Coverage: 80%)
Sequence domains:
Structure domains:
Regulatory protein MIG1
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X25
Spacegroup:
C2221
Expression systems:
- Drosophila melanogaster
- Not provided
