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Solution NMR

SOLUTION STRUCTURE OF THE ORIGIN DNA BINDING DOMAIN OF SV40 T-ANTIGEN, NMR, MINIMIZED AVERAGE STRUCTURE

Released:
DOI: 10.2210/pdb1tbd/pdb
PDB entry 1tbd coloured by chain, front view.
PDB entry 1tbd coloured by chain, side view.
PDB entry 1tbd coloured by chain, top view.
Source organism: Macaca mulatta polyomavirus 1
Primary publication:
Solution structure of the origin DNA-binding domain of SV40 T-antigen.
Luo X, Sanford DG, Bullock PA, Bachovchin WW
Nat Struct Biol 3 1034-9 (1996)
PMID: 8946857

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136535 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Large T antigen Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.41 KDa
Source organism: Macaca mulatta polyomavirus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: P03070 (Residues: 131-260; Coverage: 18%)
Sequence domains: Origin of replication binding protein
Structure domains: Replication Protein E1; Chain: A,

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

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Citations

12 review citations

The initiation of simian virus 40 DNA replication in vitro.
Bullock PA. (1997)
11 more

12 mentions without citation

Origins and evolution of viruses of eukaryotes: The ultimate modularity.
Koonin et al. (2015)
11 more