Function and Biology Details
Reaction catalysed:
Succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H(2)O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family
- Hexapeptide repeat
- Hexapeptide transferase, conserved site
- Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1
- Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily
- Trimeric LpxA-like superfamily
Structure analysis Details
Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157438 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
Molecule details ›
Chains: A, B, C
Length: 259 amino acids
Theoretical weight: 28.25 KDa
Source organism: Mycobacterium tuberculosis variant bovis
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains:
Length: 259 amino acids
Theoretical weight: 28.25 KDa
Source organism: Mycobacterium tuberculosis variant bovis
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P56220 (Residues: 1-259; Coverage: 95%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RUH2R
Spacegroup:
P21
Expression system: Escherichia coli BL21(DE3)
