› 1tia

X-ray diffraction
2.1Å resolution

AN UNUSUAL BURIED POLAR CLUSTER IN A FAMILY OF FUNGAL LIPASES

Released:
DOI: 10.2210/pdb1tia/pdb
PDB entry 1tia coloured by chain, front view.
PDB entry 1tia coloured by chain, side view.
PDB entry 1tia coloured by chain, top view.
Source organism: Penicillium camemberti
Primary publication:
An unusual buried polar cluster in a family of fungal lipases.
Derewenda U, Swenson L, Green R, Wei Y, Dodson GG, Yamaguchi S, Haas MJ, Derewenda ZS
Nat Struct Biol 1 36-47 (1994)
PMID: 7656005

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158421 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Secreted mono- and diacylglycerol lipase A Chain: A
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 30.21 KDa
Source organism: Penicillium camemberti
Expression system: Not provided
UniProt:
  • Canonical: P61870 (Residues: 27-305; Coverage: 100%)
Gene name: mdlA
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P1
Unit cell:
a: 45.57Å b: 47.1Å c: 33.5Å
α: 79.05° β: 112.14° γ: 70.28°
R-values:
R R work R free
0.19 0.19 not available
Expression system: Not provided

Quick links

Citations

8 review citations

Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications of lipases.
Jaeger et al. (1999)
7 more

4 mentions without citation

Carboxylic ester hydrolases: Classification and database derived from their primary, secondary, and tertiary structures.
Chen et al. (2016)
3 more