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X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF A KUNITZ-TYPE TRYPSIN INHIBITOR FROM ERYTHRINA CAFFRA SEEDS

Released:
DOI: 10.2210/pdb1tie/pdb
PDB entry 1tie coloured by chain, front view.
PDB entry 1tie coloured by chain, side view.
PDB entry 1tie coloured by chain, top view.
Source organism: Erythrina caffra
Primary publication:
Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina caffra seeds.
Onesti S, Brick P, Blow DM
J Mol Biol 217 153-76 (1991)
PMID: 1988676

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140830 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trypsin inhibitor DE-3 Chain: A
Molecule details ›
Chain: A
Length: 172 amino acids
Theoretical weight: 19.3 KDa
Source organism: Erythrina caffra
Expression system: Not provided
UniProt:
  • Canonical: P09943 (Residues: 1-172; Coverage: 100%)
Sequence domains: Trypsin and protease inhibitor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P6522
Unit cell:
a: 73.4Å b: 73.4Å c: 143Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.208 not available
Expression system: Not provided

Quick links

Citations

4 review citations

Natural protein proteinase inhibitors and their interaction with proteinases.
Bode et al. (1992)
3 more

16 mentions without citation

Tools for integrated sequence-structure analysis with UCSF Chimera.
Meng et al. (2006)
15 more