› 1tkj

X-ray diffraction
1.15Å resolution

Streptomyces griseus aminopeptidase complexed with D-Methionine

Released:
DOI: 10.2210/pdb1tkj/pdb
PDB entry 1tkj coloured by chain, front view.
PDB entry 1tkj coloured by chain, side view.
PDB entry 1tkj coloured by chain, top view.
Source organism: Streptomyces griseus
Entry authors: Reiland V, Gilboa R, Spungin-Bialik A, Schomburg D, Shoham Y, Blumberg S, Shoham G

Function and Biology Details

Reaction catalysed: 
Release of an N-terminal amino acid with a preference for large hydrophobic amino-terminus residues
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160427 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminopeptidase S Chain: A
Molecule details ›
Chain: A
Length: 284 amino acids
Theoretical weight: 29.75 KDa
Source organism: Streptomyces griseus
UniProt:
  • Canonical: P80561 (Residues: 46-329; Coverage: 71%)
Gene name: SGR_5809
Sequence domains: Peptidase family M28
Structure domains: Zn peptidases

Ligands and Environments

3 bound ligands:
Ligand ZN 2 x ZN
Ligand CA 1 x CA
Ligand MED 1 x MED
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12B
Spacegroup: P41212
Unit cell:
a: 60.962Å b: 60.962Å c: 144.705Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.117 0.117 0.151

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